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SNAI2 Antibody - middle region : Biotin (ARP33302_P050-Biotin)

Product Specifications

Gene Name

Snail homolog 2 (Drosophila)

Gene Aliases

SLUG, WS2D, SLUGH, SLUGH1, SNAIL2

Gene ID

6591

Swiss Prot

O43623

Accession Number

NP_003059

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SNAI2

Target

SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

SAT1; TRIM23; PPP2R2D; PPP6R3; STUB1; TJP2; UBC; TP53; PSMD3; PSMD1; PSMC1; PSMA3; PPP2CB; GSK3B; MDM2; APP; KDM1A; HDAC1; CHD4; Sin3a; HDAC2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Yeast: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Moody, S.E., (2005) Cancer Cell 8 (3), 197-209

Shipping Conditions

Wet Ice

Protein Length

268

NCBI Gene Symbol

SNAI2

NCBI GB Accession Number

SNAI2

Host or Source

Rabbit

Protein Name

Zinc finger protein SNAI2

Nucleotide Accession Number

NM_003068

Peptide Sequence

SDTSSKDHSGSESPISDEEERLQSKLSDPHAIEAEKFQCNLCNKTYSTFS

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