SIAH2 Antibody - middle region : Biotin (ARP33290_P050-Biotin)

Product Specifications

Gene Name

Siah E3 ubiquitin protein ligase 2

Gene Aliases

HSiah2

Gene ID

6478

Swiss Prot

O43255

Accession Number

NP_005058

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SIAH2

Target

SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

EGLN3; XAF1; HIPK2; UBE2D1; UBE2L6; SIAH2; UBE2D3; UBC; PPP1R13B; TP53BP2; NFE2L2; USP19; AR; UBE2I; STAT3; MYD88; EEF1D; CCBE1; SETD2; HIPK3; TNK2; KAT5; KAT2B; UBE2D2; TPX2; PML; ATN1; PSMD4; PPP1R12A; EGLN2; SH3RF1; EGLN1; DYRK2; PPP1CC; AFF1; DCC; CEB

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

SIAH2 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.