RXRA Antibody - C-terminal region : Biotin (ARP33248_P050-Biotin)
Product Specifications
Gene Name
Retinoid X receptor, alpha
Gene Aliases
NR2B1
Gene ID
6256
Swiss Prot
P19793
Accession Number
NP_002948
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human RXRA
Target
Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. RXRA is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators.Retinoid X receptors (RXRs) and retinoic acid receptors (RARs), are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors exert their action by binding, as homodimers or heterodimers, to specific sequences in the promoters of target genes and regulating their transcription. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
PPARG; VDR; NCOA1; NSD1; UBC; NR1I3; NCOA4; THRB; THRA; ALOX15B; RARA; PPARA; CHD9; PRKD2; NR0B2; STAT1; NR3C2; SMAD2; GK; JAZF1; ACVR1B; NR1I2; NCOA2; PSMC5; RAD54L2; ARID5A; PML; SUMO1; ESR2; ESR1; BHLHE40; BHLHE41; NR4A1; EP300; NCOR1; NCOA6; NCOA3; TR
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
51kDa
References & Citations
Lamhonwah, A.M., (2008) Mol. Cell. Biol. 28 (11), 3817-3829
Shipping Conditions
Wet Ice
Protein Length
462
NCBI Gene Symbol
RXRA
NCBI GB Accession Number
RXRA
Host or Source
Rabbit
Protein Name
Retinoic acid receptor RXR-alpha
Nucleotide Accession Number
NM_002957
Peptide Sequence
MDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQ
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