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DPF2 Antibody - middle region : Biotin (ARP33222_P050-Biotin)

Product Specifications

Gene Name

D4, zinc and double PHD fingers family 2

Gene Aliases

REQ, CSS7, UBID4, ubi-d4

Gene ID

5977

Swiss Prot

Q92785

Accession Number

NP_006259

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DPF2

Target

DPF2 may be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. DPF2 might also have a role in the development and maturation of lymphoid cells.The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.

Partner Proteins

LNX1; LDOC1; UBC; RNF2; BMI1; UPF2; YAP1; HIST3H3; EPAS1; ZNF212; TP53BP1; FHL2; NCSTN; DDX18; COPS5; CUL3; SMARCC1; SMARCA4; SMARCA2; RELA; NFKB1; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; HIST1H3A; ARID1A; HDAC1; ESRRG; ESRRB; ESRRA; REL; NFKB2; SMARCB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DPF2 is supported by BioGPS gene expression data to be expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

391

NCBI Gene Symbol

DPF2

NCBI GB Accession Number

DPF2

Host or Source

Rabbit

Protein Name

Zinc finger protein ubi-d4

Nucleotide Accession Number

NM_006268

Peptide Sequence

RRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHY

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