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DPF2 Antibody - middle region : HRP (ARP33222_P050-HRP)

Product Specifications

Gene Name

D4, zinc and double PHD fingers family 2

Gene Aliases

REQ, CSS7, UBID4, ubi-d4

Gene ID

5977

Swiss Prot

Q92785

Accession Number

NP_006259

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human DPF2

Target

DPF2 may be a transcription factor required for the apoptosis response following survival factor withdrawal from myeloid cells. DPF2 might also have a role in the development and maturation of lymphoid cells.The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.

Partner Proteins

LNX1; LDOC1; UBC; RNF2; BMI1; UPF2; YAP1; HIST3H3; EPAS1; ZNF212; TP53BP1; FHL2; NCSTN; DDX18; COPS5; CUL3; SMARCC1; SMARCA4; SMARCA2; RELA; NFKB1; SUMO2; SMARCE1; SMARCD1; SMARCC2; Bcl7b; HIST1H3A; ARID1A; HDAC1; ESRRG; ESRRB; ESRRA; REL; NFKB2; SMARCB1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

DPF2 is supported by BioGPS gene expression data to be expressed in NCIH226

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Olsen, J.V., (2006) Cell 127 (3), 635-648

Shipping Conditions

Wet Ice

Protein Length

391

NCBI Gene Symbol

DPF2

NCBI GB Accession Number

DPF2

Host or Source

Rabbit

Protein Name

Zinc finger protein ubi-d4

Nucleotide Accession Number

NM_006268

Peptide Sequence

RRGKGKSKGKGVGSARKKLDASILEDRDKPYACDICGKRYKNRPGLSYHY

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