RB1 Antibody - C-terminal region : Biotin (ARP33212_P050-Biotin)

Product Specifications

Gene Name

Retinoblastoma 1

Gene Aliases

RB, pRb, OSRC, pp110, p105-Rb, PPP1R130, p110-RB1

Gene ID

5925

Swiss Prot

P06400

Accession Number

NP_000312

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human RB1

Target

Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.

Partner Proteins

RAF1; E2F1; ABL1; HDAC1; KDM2A; SMARCA4; USP7; UBC; DYRK1A; NEFM; DYRK1B; MAGEA11; ENC1; PPP1CA; CDKN1C; CDKN1A; CDK6; CDK4; CDK2; CCNE1; CCNA2; CCND1; HDAC11; PAX5; HIF1A; E2F4; CEBPE; CCNA1; SUMO1; UBE2I; TFAP2A; CDK3; CDK1; CCNC; CCNB1; MRPS18B; SUMO2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

RB1 is strongly supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.