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NFS1 Antibody - middle region : Biotin (ARP33115_T100-Biotin)

Product Specifications

Gene Name

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

Gene Aliases

IscS, NIFS, HUSSY-08

Gene ID

9054

Swiss Prot

Q9Y697

Accession Number

NP_066923

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NFS1

Target

Iron-sulfur clusters are required for the function of many cellular enzymes. The protein encoded by this gene supplies inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded protein belongs to the class-V family of pyridoxal phosphate-dependent aminotransferases. Two transcript variants encoding two different isoforms have been found for this gene.

Partner Proteins

UBC; HDAC5

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Sample Type

NFS1 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Yeast: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

50kDa

References & Citations

Stanchi, F., et al., (2001) Yeast 18 (1), 69-80

Shipping Conditions

Wet Ice

Protein Length

457

NCBI Gene Symbol

NFS1

NCBI GB Accession Number

NFS1

Host or Source

Rabbit

Protein Name

Cysteine desulfurase, mitochondrial

Nucleotide Accession Number

NM_021100

Peptide Sequence

TTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLV

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