MAP4K5 Antibody - middle region : Biotin (ARP33101_P050-Biotin)

Product Specifications

Gene Name

Mitogen-activated protein kinase kinase kinase kinase 5

Gene Aliases

KHS, GCKR, KHS1, MAPKKKK5

Gene ID

11183

Swiss Prot

Q9Y4K4

Accession Number

NP_006566

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human MAP4K5

Target

MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Partner Proteins

CRK; ELAVL1; UBC; NEDD4; SETDB1; ZNF440; COPS5; HCK; GRB2; TANK; CRKL; TRAF2; ABL1; BCR

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 77%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

References & Citations

Wissing, J., (2007) Mol. Cell Proteomics 6 (3), 537-547

Shipping Conditions

Wet Ice

Protein Length

846

NCBI Gene Symbol

MAP4K5

NCBI GB Accession Number

MAP4K5

Host or Source

Rabbit

Protein Name

Mitogen-activated protein kinase kinase kinase kinase 5

Nucleotide Accession Number

NM_006575

Peptide Sequence

QGKSFKSDEVTQEISDETRVFRLLGSDRVVVLESRPTENPTAHSNLYILA

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