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IVNS1ABP Antibody - N-terminal region : Biotin (ARP33099_P050-Biotin)

Selected Variant

ARP33099_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Influenza virus NS1A binding protein

Gene Aliases

ND1, ARA3, NS-1, IMD70, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068

Gene ID

10625

Swiss Prot

Q9Y6Y0

Accession Number

NP_006460

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human IVNS1ABP

Target

This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.

Partner Proteins

UBC; DHX36; PARP1; ACTB; ZC3HAV1; RBMX; LARP1; DHX30; HNRNPUL1; IGF2BP1; IVNS1ABP; DDX17; HNRNPR; LRPPRC; THRAP3; G3BP2; DDX21; PABPC4; GBF1; STAU1; UPF1; POLR2A; YBX1; NCBP1; HNRNPM; MYH9; ILF3; ILF2; HSP90AB1; HSPA8; HNRNPU; HNRNPL; HNRNPK; HNRNPF; HNRN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 93%; Rat: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

72kDa

References & Citations

Wolff, T., et al., (1998) J. Virol. 72 (9), 7170-7180

Shipping Conditions

Wet Ice

Protein Length

642

NCBI Gene Symbol

IVNS1ABP

NCBI GB Accession Number

IVNS1ABP

Host or Source

Rabbit

Protein Name

Influenza virus NS1A-binding protein

Nucleotide Accession Number

NM_006469

Peptide Sequence

RAVLACCSPYLFEIFNSDSDPHGISHVKFDDLNPEAVEVLLNYAYTAQLK

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