ARID4A Antibody - C-terminal region: FITC (ARP33088_T100-FITC)
Product Specifications
Gene Name
AT rich interactive domain 4A (RBP1-like)
Gene Aliases
RBP1, RBBP1, RBP-1, RBBP-1
Gene ID
5926
Swiss Prot
P29374
Accession Number
NP_002883
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A
Target
ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
Partner Proteins
SUMO2; SUMO1; HDAC1; BRMS1; HIST2H3C; HIST4H4; UBC; CDK2; CDK1; CCNE1; CCNB1; CCNA2; CCND1; CDK4; SIN3A; SAP30; RB1; SIN3B; RBBP7; RBBP4; ARID4B; HDAC3; EID1; HDAC2; ING2; RBL1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
143kDa
Shipping Conditions
Wet Ice
Protein Length
1257
NCBI Gene Symbol
ARID4A
Protein Name
AT-rich interactive domain-containing protein 4A
Nucleotide Accession Number
NM_002892
Curated Selection
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