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ARID4A Antibody - C-terminal region : FITC (ARP33088_T100-FITC)

Selected Variant

ARP33088_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

AT rich interactive domain 4A (RBP1-like)

Gene Aliases

RBP1, RBBP1, RBP-1, RBBP-1

Gene ID

5926

Swiss Prot

P29374

Accession Number

NP_002883

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A

Target

ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.

Partner Proteins

SUMO2; SUMO1; HDAC1; BRMS1; HIST2H3C; HIST4H4; UBC; CDK2; CDK1; CCNE1; CCNB1; CCNA2; CCND1; CDK4; SIN3A; SAP30; RB1; SIN3B; RBBP7; RBBP4; ARID4B; HDAC3; EID1; HDAC2; ING2; RBL1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 100%; Guinea Pig: 79%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 86%; Rabbit: 86%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

143kDa

References & Citations

Meehan, W.J., et al., (2004) J. Biol. Chem. 279 (2), 1562-1569

Shipping Conditions

Wet Ice

Protein Length

1257

NCBI Gene Symbol

ARID4A

NCBI GB Accession Number

ARID4A

Host or Source

Rabbit

Protein Name

AT-rich interactive domain-containing protein 4A

Nucleotide Accession Number

NM_002892

Peptide Sequence

NSSKCTPVKHLNVSKPQKLARSPARISPHIKDGEKDKHREKHPNSSPRTY

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