ENG Antibody - N-terminal region : Biotin (ARP33068_T100-Biotin)
Selected Variant
ARP33068_T100-Biotin
Size: 100 µL
Product Specifications
Gene Name
Endoglin
Gene Aliases
END, HHT1, ORW1
Gene ID
2022
Swiss Prot
P17813
Accession Number
NP_000109
Host
Rabbit
Reactivity
Human, Mouse, Rat, Guinea Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ENG
Target
Endoglin is a homodimeric transmembrane glycoprotein highly expressed by endothelial cells. It is a component of the transforming growth factor beta receptor complex since it binds TGFB1 and TGFB3 with high affinity. Mutations in the endoglin gene produce hereditary hemorrhagic telangiectasia.
Partner Proteins
ENG; TGFBR2; TGFBR1; TGFB3; TGFB1; ACVRL1; TUFM; TCTEX1D4; TGFBR3; TGFB2; INHBA; BMP7; BMP2; ACVR2A; ACVR1; ACVR2B
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Guinea Pig: 91%; Human: 100%; Mouse: 91%; Rat: 91%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
68kDa
References & Citations
Sanz-Rodriguez, F., et al., (2004) J. Biol. Chem. 279 (31), 32858-32868
Shipping Conditions
Wet Ice
Protein Length
625
NCBI Gene Symbol
ENG
NCBI GB Accession Number
ENG
Host or Source
Rabbit
Protein Name
Endoglin
Nucleotide Accession Number
NM_000118
Peptide Sequence
ILEVHVLFLEFPTGPSQLELTLQASKQNGTWPREVLLVLSVNSSVFLHLQ
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