POU3F3 Antibody - N-terminal region : Biotin (ARP33062_P050-Biotin)
Product Specifications
Gene Name
POU class 3 homeobox 3
Gene Aliases
BRN1, OTF8, oct-8, SNIBFIS, brain-1
Gene ID
5455
Swiss Prot
P20264
Accession Number
NP_006227
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human POU3F3
Target
POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction; the enhancer element contains the octamer motif (5'-ATTTGCAT-3') .POU3F3 is a member of the class III POU family of transcription factors (see POU3F1; MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Partner Proteins
Dlg4; SOX8; PPP1R15A; SOX10; SOX11; POU3F4
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
POU3F3 is supported by BioGPS gene expression data to be expressed in OVCAR3
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
References & Citations
Wissmuller, S., (2006) (er) Nucleic Acids Res. 34 (6), 1735-1744
Shipping Conditions
Wet Ice
Protein Length
500
NCBI Gene Symbol
POU3F3
NCBI GB Accession Number
POU3F3
Host or Source
Rabbit
Protein Name
POU domain, class 3, transcription factor 3
Nucleotide Accession Number
NM_006236
Peptide Sequence
GGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQGAMAA
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