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SOX18 Antibody - middle region : Biotin (ARP33056_P050-Biotin)

Product Specifications

Gene Name

SRY (sex determining region Y) -box 18

Gene Aliases

HLTS, HLTRS

Gene ID

54345

Swiss Prot

P35713

Accession Number

NP_060889

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SOX18

Target

SOX18 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Partner Proteins

GKAP1; MECP2; MEF2C; HMGB1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IF, WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Spataro, V., et al., (2005) Arterioscler. Thromb. Vasc. Biol. 25 (11), 2398-2403

Shipping Conditions

Wet Ice

Protein Length

384

NCBI Gene Symbol

SOX18

NCBI GB Accession Number

SOX18

Host or Source

Rabbit

Protein Name

Transcription factor SOX-18

Nucleotide Accession Number

NM_018419

Peptide Sequence

RTAPPAAPLAGLYYGTLGTPGPYPGPLSPPPEAPPLESAEPLGPAADLWA

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