PLD2 Antibody - middle region : Biotin (ARP33044_P050-Biotin)
Product Specifications
Gene Name
Phospholipase D2
Gene Aliases
PLD1C
Gene ID
5338
Swiss Prot
O14939
Accession Number
NP_002654
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PLD2
Target
Phosphatidylcholine (PC) -specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.Phosphatidylcholine (PC) -specific phospholipases D (PLDs; EC 3.1.4.4) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-14 AF033850.1 61-74 15-614 BC015033.1 1-600 615-1279 BC056871.1 549-1213 1280-1830 BC015033.1 1266-1816 1831-1995 BC056871.1 1765-1929 1996-3489 BC015033.1 1982-3475
Partner Proteins
UBC; RPS6KB1; CUL3; AQP3; RPTOR; PEA15; PIP5K1A; STXBP1; DPYSL2; BIN1; MTOR; CAV1; AMPH; OPRM1; ALDOC; GM2A; PRKCD; PRKCA; PLCG1; LCK; GAPDH; FYN; EGFR; CSK; ALDOA; ARF1; ACTB; ACTN1; CAV2; SRC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Horse: 92%; Human: 100%; Pig: 92%; Rat: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
106kDa
References & Citations
Gorshkova, I., (2008) J. Biol. Chem. 283 (17), 11794-11806
Shipping Conditions
Wet Ice
Protein Length
933
NCBI Gene Symbol
PLD2
NCBI GB Accession Number
PLD2
Host or Source
Rabbit
Protein Name
Phospholipase D2
Nucleotide Accession Number
NM_002663
Peptide Sequence
DLHYRLTDLGDSSESAASQPPTPRPDSPATPDLSHNQFFWLGKDYSNLIT
Curated Selection
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