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SUFU Antibody - middle region : Biotin (ARP33018_P050-Biotin)

Product Specifications

Gene Name

Suppressor of fused homolog (Drosophila)

Gene Aliases

SUFUH, JBTS32, SUFUXL, PRO1280

Gene ID

51684

Swiss Prot

Q9UMX1

Accession Number

NP_057253

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human SUFU

Target

SUFU is a component of the Sonic hedgehog (SHH; MIM 600725) /Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes. SUFU encodes a component of the sonic hedgehog (SHH; MIM 600725) /patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

ZNF747; FBXL17; GLIS3; UBC; GLI1; HDX; SAP18; RCN3; PIAS1; PEX26; ZNF764; STK36; ZNF446; QPRT; SETDB1; MID1IP1; RNF19A; SUFU; ZNF219; ZNF263; BTRC; LAMTOR3; NCOA3; HMGA1; GLI3; GLI2; HNRNPA1; LGALS3; RBPJ

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

54kDa

References & Citations

Lee, D.Y., (2007) Proc. Natl. Acad. Sci. U.S.A. 104 (51), 20350-20355

Shipping Conditions

Wet Ice

Protein Length

484

NCBI Gene Symbol

SUFU

NCBI GB Accession Number

SUFU

Host or Source

Rabbit

Protein Name

Suppressor of fused homolog

Nucleotide Accession Number

NM_016169

Peptide Sequence

NGQGILELLRTVPIAGGPWLITDMRRGETIFEIDPHLQERVDKGIETDGS

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