TTRAP Antibody - middle region : Biotin (ARP33010_P050-Biotin)

Product Specifications

Gene Name

Tyrosyl-DNA phosphodiesterase 2

Gene Aliases

EAP2, AD022, EAPII, TTRAP, hTDP2, dJ30M3.3

Gene ID

51567

Swiss Prot

O95551

Accession Number

NP_057698

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TTRAP

Target

The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Partner Proteins

UBC; SRPK2; SUMO1; SUMO2; SUMO3; TAP1; SKIL; ATXN1; PSEN1; SMAD3; EPS8; DLX3; ATP5G2; C2orf88; JAM2; SNX13; AKAP9; RAB11A; PARK7; MAPK6; UBE2I; TRAF5; TRAF6; TRAF3; TRAF2; FLI1; TNFRSF1B; ETS2; ETS1; TNFRSF8; CD40; HTNVsSgp1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

TDP2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

41kDa

References & Citations

Pei, H., et al., (2003) Oncogene 22 (18), 2699-2709

Shipping Conditions

Wet Ice

Protein Length

362

NCBI Gene Symbol

TDP2

NCBI GB Accession Number

TDP2

Host or Source

Rabbit

Protein Name

Tyrosyl-DNA phosphodiesterase 2

Nucleotide Accession Number

NM_016614

Peptide Sequence

IPPYYSYLKKRSSNYEIITGHEEGYFTAIMLKKSRVKLKSQEIIPFPSTK

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