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PCYOX1 Antibody - C-terminal region : HRP (ARP33007_T100-HRP)

Product Specifications

Gene Name

Prenylcysteine oxidase 1

Gene Aliases

PCL1

Gene ID

51449

Swiss Prot

Q9UHG3

Accession Number

NP_057381

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PCYOX1

Target

Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.

Partner Proteins

UBC; SLC9A3R1; NDUFV2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Cow: 83%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 83%; Rabbit: 100%; Yeast: 75%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270

Shipping Conditions

Wet Ice

Product Datasheet

Anti-PCYOX1 (ARP33007_T100-HRP) antibody

Protein Length

505

NCBI Gene Symbol

PCYOX1

NCBI GB Accession Number

PCYOX1

Host or Source

Rabbit

Protein Name

Prenylcysteine oxidase 1

Nucleotide Accession Number

NM_016297

Peptide Sequence

IFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYY

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