PCYOX1 Antibody - C-terminal region : HRP (ARP33007_T100-HRP)
Selected Variant
ARP33007_T100-HRP
Size: 100 µL
Product Specifications
Gene Name
Prenylcysteine oxidase 1
Gene Aliases
PCL1
Gene ID
51449
Swiss Prot
Q9UHG3
Accession Number
NP_057381
Host
Rabbit
Reactivity
Human, Cow, Dog, Horse, Pig, Rabbit, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human PCYOX1
Target
Prenylated proteins contain one of two isoprenoid lipids, either the 15-carbon farnesyl or the 20-carbon geranylgeranyl, covalently attached to cysteine residues at or near their C terminus. PCYOX1 is capable of cleaving the thioether bond of prenylcysteines. The enzyme was isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa. This is a specific enzyme involved in prenylcysteine metabolism in mammalian cells, most likely comprising the final step in the degradation of prenylated proteins.
Partner Proteins
UBC; SLC9A3R1; NDUFV2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 83%; Dog: 86%; Horse: 86%; Human: 100%; Pig: 83%; Rabbit: 100%; Yeast: 75%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
References & Citations
Clark, H.F., et al., (2003) Genome Res. 13 (10), 2265-2270
Shipping Conditions
Wet Ice
Protein Length
505
NCBI Gene Symbol
PCYOX1
NCBI GB Accession Number
PCYOX1
Host or Source
Rabbit
Protein Name
Prenylcysteine oxidase 1
Nucleotide Accession Number
NM_016297
Peptide Sequence
IFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYY
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