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JMJD2C Antibody - C-terminal region : FITC (ARP32974_P050-FITC)

Selected Variant

ARP32974_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Lysine (K) -specific demethylase 4C

Gene Aliases

GASC1, JHDM3C, JMJD2C, TDRD14C

Gene ID

23081

Swiss Prot

F5H347

Accession Number

NP_001140167

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human JMJD2C

Target

JMJD2C is a member of the Jumonji domain 2 (JMJD2) family. It contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma.

Partner Proteins

UBC; HIST2H3C; HDAC3; PPARG; HDAC1; H3F3A; HIST1H3A; KDM4C; KDM4A

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

Shipping Conditions

Wet Ice

Protein Length

813

NCBI Gene Symbol

KDM4C

NCBI GB Accession Number

KDM4C

Host or Source

Rabbit

Protein Name

Lysine-specific demethylase 4C Ensembl ENSP00000445427

Nucleotide Accession Number

NM_001146695

Peptide Sequence

CLCNLRGGALKQTKNNKWAHVMCAVAVPEVRFTNVPERTQIDVGRIPLQR

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