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PBXIP1 Antibody - N-terminal region : FITC (ARP32948_P050-FITC)

Product Specifications

Gene Name

Pre-B-cell leukemia homeobox interacting protein 1

Gene Aliases

HPIP

Gene ID

57326

Swiss Prot

Q96AQ6

Accession Number

NP_065385

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PBXIP1

Target

PBXIP1 is the regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.

Partner Proteins

MORF4L1; SGTA; GMCL1; DEF6; UBQLN1; DAXX; CCNC; UBC; SUMO1; NEDD8; RNF2; CCDC53; ZMYND8; MDFI; UBQLN4; PRKAA2; GRB2; PCBD2; ZZZ3; BRPF1; CCDC85B; DPPA2; TSNAX

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 92%; Human: 100%; Mouse: 92%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

81kDa

References & Citations

Lim, J., (2006) Cell 125 (4), 801-814

Shipping Conditions

Wet Ice

Product Datasheet

Anti-PBXIP1 (ARP32948_P050-FITC) antibody

Protein Length

731

NCBI Gene Symbol

PBXIP1

NCBI GB Accession Number

PBXIP1

Host or Source

Rabbit

Protein Name

Pre-B-cell leukemia transcription factor-interacting protein 1

Nucleotide Accession Number

NM_020524

Peptide Sequence

AGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQ

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