REXO4 Antibody - middle region : FITC (ARP32934_P050-FITC)
Selected Variant
ARP32934_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
Gene Aliases
REX4, XPMC2, XPMC2H
Gene ID
57109
Swiss Prot
Q9GZR2
Accession Number
NP_065118
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human REXO4
Target
The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE) . QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Partner Proteins
UBC; SIRT7; ESR2; ESR1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
References & Citations
Mehrle, A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006)
Shipping Conditions
Wet Ice
Protein Length
422
NCBI Gene Symbol
REXO4
NCBI GB Accession Number
REXO4
Host or Source
Rabbit
Protein Name
RNA exonuclease 4
Nucleotide Accession Number
NM_020385
Peptide Sequence
PADIEAAIGPEAAKIARKQLGQSEGSVSLSLVKEQAFGGLTRALALDCEM
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