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HR Antibody - middle region : Biotin (ARP32907_P050-Biotin)

Product Specifications

Gene Name

Hairless homolog (mouse)

Gene Aliases

AU, MUHH, ALUNC, HYPT4, MUHH1, HSA277165

Gene ID

55806

Swiss Prot

O43593

Accession Number

NP_005135

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HR

Target

HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

VDR; TBL1X; TRIM27; RARB; RARA; HDAC1; HDAC5; HDAC3; HMGB1; HDAC2; THRA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 77%; Dog: 85%; Human: 100%; Mouse: 77%; Pig: 85%; Rat: 77%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

127kDa

References & Citations

Xie, Z., et al., (2006) Endocrinology 147 (1), 314-323

Shipping Conditions

Wet Ice

Protein Length

1189

NCBI Gene Symbol

HR

NCBI GB Accession Number

HR

Host or Source

Rabbit

Protein Name

Protein hairless

Nucleotide Accession Number

NM_005144

Peptide Sequence

RVWAPGDAGQQKESTQKTPPTPQPSCNGDTHRTKSIKEETPDSAETPAED

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