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HES6 Antibody - C-terminal region : Biotin (ARP32896_T100-Biotin)

Selected Variant

ARP32896_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Hairy and enhancer of split 6 (Drosophila)

Gene Aliases

HES-6, bHLHb41, bHLHc23, C-HAIRY1

Gene ID

55502

Swiss Prot

Q96HZ4

Accession Number

NP_061115

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human HES6

Target

HES6 belongs to a subfamily of basic helix-loop-helix transcription factors that includes Drosophila Hairy and Enhancer of split genes. Like other members of the family, HES6 features the WRPW motif which is consisted just of four amino acids at its C-terminus. It is expressed by both undifferentiated and differentiated cells and is an inhibitor of Hes1. HES6 supports Mash1 activity and promotes cell differentiation.

Partner Proteins

TWIST1; CREBBP; TLE1; HES1; CSNK2A1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Concentration

0.5 mg/ml

Homology

Dog: 86%; Human: 100%; Mouse: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Kang, S.A., (2005) Biochem. Biophys. Res. Commun. 332 (1), 33-36

Shipping Conditions

Wet Ice

Protein Length

224

NCBI Gene Symbol

HES6

NCBI GB Accession Number

HES6

Host or Source

Rabbit

Protein Name

Transcription cofactor HES-6

Nucleotide Accession Number

NM_018645

Peptide Sequence

PPGPGDDLCSDLEEAPEAELSQAPAEGPDLVPAALGSLTTAQIARSVWRP

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