ALF Antibody - N-terminal region : FITC (ARP32837_P050-FITC)
Product Specifications
Gene Name
General transcription factor IIA, 1-like
Gene Aliases
ALF
Gene ID
11036
Swiss Prot
Q9UNN4
Accession Number
NP_751946
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ALF
Target
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involves the effects of TFIIA on the interaction between TATA-binding protein (TBP) and DNA. ALF is a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology.
Partner Proteins
GAB1; NKX2-3; ZBTB3; TLX3; MAFF; RBFOX2; HMG20A; PAX9; SIX6; MAFG; HOXC11; HOXC9; HOXA5; TLX2; EMX2; EMX1; CEBPE; ATF4; ASCL3; GTF2A2; SUB1; ID3; CSNK2A2; CSNK2A1; TBP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 92%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Rabbit: 91%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
References & Citations
Upadhyaya, A.B., et al., (2002) J. Biol. Chem. 277 (37), 34208-34216
Shipping Conditions
Wet Ice
Protein Length
453
NCBI Gene Symbol
GTF2A1L
NCBI GB Accession Number
GTF2A1L
Host or Source
Rabbit
Protein Name
TFIIA-alpha and beta-like factor
Nucleotide Accession Number
NM_172196
Peptide Sequence
VIPAGRTLPSFTTAELGTSNSSANFTFPGYPIHVPAGVTLQTVSGHLYKV
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