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TCERG1 Antibody - middle region : HRP (ARP32830_P050-HRP)

Product Specifications

Gene Name

Transcription elongation regulator 1

Gene Aliases

Urn1, CA150, TAF2S

Gene ID

10915

Swiss Prot

O14776

Accession Number

NP_006697

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TCERG1

Target

TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.

Partner Proteins

CEP76; UBC; RPA3; RPA2; RPA1; EED; WIPF2; PSPC1; WWOX; EVL; CYFIP2; BRD4; SF3B1; SF3B3; CYFIP1; U2AF2; WBP4; CPSF6; NUDT21; SF3B2; SF3A3; DIAPH2; DIAPH1; FMNL1; SF3A1; WASF2; ABI1; SF3A2; SF1; WAS; SFPQ; NONO; HNRNPU; HNRNPK; JUNB; FN1; Dlg4; ITGA4; PSAP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

TCERG1 is supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

124kDa

References & Citations

Pearson, J.L., (2008) J. Biol. Chem. 283 (12), 7949-7961

Shipping Conditions

Wet Ice

Protein Length

1098

NCBI Gene Symbol

TCERG1

NCBI GB Accession Number

TCERG1

Host or Source

Rabbit

Protein Name

Transcription elongation regulator 1

Nucleotide Accession Number

NM_006706

Peptide Sequence

LLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIK

Frequently Asked Questions

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