PCK1 Antibody - N-terminal region : Biotin (ARP32800_P050-Biotin)

PCK1 is a main control point for the regulation of gluconeogenesis. PCK1, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of PCK1 can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

UBC; FBXO25; C1R; APP; CUL5; BAG6; TCP1; TCEB1; SKP1; RPS15A; RPS6; RPS3A; RPS3; RPLP0; RPL4; PSMD12; PSMD2; PSMC5; PSMC4; PSMC2; PSMC1; PSMB7; PSMB4; PSMB1; PSMA5; PSMA2; PCK1; LDHA; HSPD1; HSPA1L; DNAJA1; HLA-C; HLA-B; GNAS; GNAI1; GNA12; FASN; EP300; T

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.