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ACAT2 Antibody - middle region : HRP (ARP32791_T100-HRP)

Product Specifications

Gene Name

Acetyl-CoA acetyltransferase 2

Gene ID

39

Swiss Prot

Q16146

Accession Number

NP_005882

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ACAT2

Target

Acetyl-Coenzyme A acetyltransferase 2 is an enzyme involved in lipid metabolism. Reported patients with ACAT2 deficiency have shown severe mental retardation and hypotonus. The ACAT2 gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.

Partner Proteins

LNX1; ACAT2; UBC; SUMO2; OLA1; TUBB3; PAPSS1; UBA3; PKM; HMGB3; HEXA; FH; ALDH9A1; AHCY; BAG3; TTC39C; PSAT1; SSU72; DAK; VASP; TERF1; CDX2; CSNK2A1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

ACAT2 is supported by BioGPS gene expression data to be expressed in K562

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 86%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 79%; Rat: 79%; Yeast: 82%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Sakashita, N., et al., (2003) Lab.Invest.83 (11),1569-1581

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ACAT2 (ARP32791_T100-HRP) antibody

Protein Length

397

NCBI Gene Symbol

ACAT2

NCBI GB Accession Number

ACAT2

Host or Source

Rabbit

Protein Name

Acetyl-CoA acetyltransferase, cytosolic

Nucleotide Accession Number

NM_005891

Peptide Sequence

VLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMS

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