MXD4 Antibody - N-terminal region : Biotin (ARP32777_P050-Biotin)
Product Specifications
Gene Name
MAX dimerization protein 4
Gene Aliases
MAD4, MST149, MSTP149, bHLHc12
Gene ID
10608
Swiss Prot
Q14582
Accession Number
NP_006445
Host
Rabbit
Reactivity
Human, Mouse, Cow, Dog, Guinea Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human MXD4
Target
MXD4 is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
Partner Proteins
TCP10L; UBC; SHBG; SIN3A; MLX; MAX; SMC3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Sheep: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24kDa
References & Citations
Jiang, D.J., et al., (2004) J. Biochem. Mol. Biol. 37 (4), 402-407
Shipping Conditions
Wet Ice
Protein Length
209
NCBI Gene Symbol
MXD4
NCBI GB Accession Number
MXD4
Host or Source
Rabbit
Protein Name
Max dimerization protein 4
Nucleotide Accession Number
NM_006454
Peptide Sequence
SLLILLEAAEYLERRDREAEHGYASVLPFDGDFAREKTKAAGLVRKAPNN
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