Nr1h3 Antibody - C-terminal region : HRP (ARP32674_P050-HRP)
Selected Variant
ARP32674_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Nuclear receptor subfamily 1, group H, member 3
Gene Aliases
Un, LXR, RLD1, Unr1, AU018371
Gene ID
22259
Swiss Prot
Q9Z0Y9
Accession Number
NP_038867
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Target
Nr1h3 is an orphan receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Nr1h3 plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.
Partner Proteins
Ncor1; Ppargc1b; Zfp111; Rxrg; Rxra; Ppargc1a; Ubc
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
50kDa
Shipping Conditions
Wet Ice
Protein Length
445
NCBI Gene Symbol
NR1H3
NCBI GB Accession Number
Nr1h3
Host or Source
Rabbit
Protein Name
Oxysterols receptor LXR-alpha
Nucleotide Accession Number
NM_013839
Peptide Sequence
LLIAISIFSADRPNVQDQLQVERLQHTYVEALHAYVSINHPHDPLMFPRM
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC683226-100 1x 100 µL
Prohibitin (Mitochondrial Marker) (PHB/3226), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC681203-100 1x 100 µL
Smooth Muscle Actin (ACTA2/791 +1A4), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
EK0459 96 Well With Removable Strips
Human MMP-2 ELISA Kit PicoKine®
Sign In for Pricing
View Details ![Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31]](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82bf9/imageurl/et7107-48.webp)
ET7107-48 100 µL
Biglycan Recombinant Rabbit Monoclonal Antibody [JB71-31]
Sign In for Pricing
View Details 
BNC401764-100 1x 100 µL
MMP9 (Matrix Metalloproteinase 9) (2C3), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
A01238-2-APC 100 µg/Vial
Anti-Lamin B Receptor/LBR Antibody Picoband®, APC Conjugate
Sign In for Pricing
View Details