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GRM6 Antibody - C-terminal region : HRP (ARP32597_P050-HRP)

Selected Variant

ARP32597_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Glutamate receptor, metabotropic 6

Gene Aliases

MGlu6, CSNB1B, GPRC1F, MGLUR6

Gene ID

2916

Swiss Prot

O15303

Accession Number

NP_000834

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GRM6

Target

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. GRM6 is part of Group III which is linked to the inhibition of the cyclic AMP cascade.

Partner Proteins

GNAO1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

95kDa

References & Citations

Hashimoto, T., et al., (1997) Eur. J. Neurosci. 9 (6), 1226-1235

Shipping Conditions

Wet Ice

Protein Length

877

NCBI Gene Symbol

GRM6

NCBI GB Accession Number

GRM6

Host or Source

Rabbit

Protein Name

Metabotropic glutamate receptor 6

Nucleotide Accession Number

NM_000843

Peptide Sequence

ITFSLTSLQVVGMIAWLGARPPHSVIDYEEQRTVDPEQARGVLKCDMSDL

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