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SND1 Antibody - N-terminal region : Biotin (ARP32563_T100-Biotin)

Product Specifications

Gene Name

Staphylococcal nuclease and tudor domain containing 1

Gene Aliases

P100, TDRD11, Tudor-SN

Gene ID

27044

Swiss Prot

Q7KZF4

Accession Number

NP_055205

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SND1

Target

SND1 was originally characterized as a transcriptional coactivator for Epstein-Barr virus nuclear antigen 2. It is a STAT6 TAD interacting protein containing staphylococcal nuclease (SN) -like domain and tudor domain. p100 . The interaction is mediated by the TAD domain of STAT6 and the SN-like domain of SND1. SND1 associates with the large subunit of RNA polymerase II and is mediating interaction between STAT6 and RNA polymerase II. It was identified as a novel coactivator for STAT6 and suggest its functions as a bridging factor between STAT6 and the basal transcription machinery

Partner Proteins

HUWE1; RAPGEF2; UBC; SUMO2; MDM2; LIN28A; SHFM1; DDX3X; EIF3CL; RPL35; RPS27; RPS26; RPS16; RPS11; RPS9; RPS6; RPS3A; RPS2; RPL23A; HNRNPU; TARDBP; UBD; RNU4-1; RNU5A-1; RNU6-1; PRPF8; RNU2-1; RNU1-1; G3BP1; VCAM1; MAK; ITGA4; FN1; CSNK2A1; SSR3; SRSF3; R

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Sample Type

SND1 is supported by BioGPS gene expression data to be expressed in Raji

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

100kDa

References & Citations

Yang, J., et al., (2002) EMBO J. 21 (18), 4950-4958

Shipping Conditions

Wet Ice

Protein Length

885

NCBI Gene Symbol

SND1

NCBI GB Accession Number

SND1

Host or Source

Rabbit

Protein Name

Staphylococcal nuclease domain-containing protein 1

Nucleotide Accession Number

NM_014390

Peptide Sequence

LPDYYLVTVMLSGIKCPTFRREADGSETPEPFAAEAKFFTESRLLQRDVQ

Frequently Asked Questions

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