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NR5A2 Antibody - middle region : FITC (ARP32524_P050-FITC)

Selected Variant

ARP32524_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Nuclear receptor subfamily 5, group A, member 2

Gene Aliases

B1F, CPF, FTF, B1F2, LRH1, LRH-1, FTZ-F1, hB1F-2, FTZ-F1beta

Gene ID

2494

Swiss Prot

O60587

Accession Number

AAD03248

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NR5A2

Target

NR5A2 binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. It may be responsable for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. It is a key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. It may also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.

Partner Proteins

NSD1; NCOA1; CREB1; UBE2I; RAD54L2; NR0B2; GPS2; ILF3; PNRC2; COPS5; PNRC1; BCKDK; NRIP1; SRC; NPPA; FTH1; ALB; SUMO1; PPARGC1A; POLR2D; EDF1; SMARCD3; PROX1; Ncoa3; Ptpn6; CTNNB1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Sheep: 86%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

Shipping Conditions

Wet Ice

Protein Length

323

NCBI Gene Symbol

NR5A2

NCBI GB Accession Number

NR5A2

Host or Source

Rabbit

Protein Name

Alpha1-fetoprotein transcription factor short variant EMBL AAD03248.1

Nucleotide Accession Number

NM_003822

Peptide Sequence

LPPTDYDRSPFVTSPISMTMLHGSLQGYQTYGHFPSRAIKSEYPDPYTSS

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