NCOA3 Antibody - middle region : HRP (ARP32487_P050-HRP)

NCOA3 is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

PSMB9; PPARG; CUL3; ARNT2; MMS19; FBXW7; SPOP; UBC; E2F1; PTEN; ESR2; ALB; NR1I2; THRB; CHUK; KANK2; ESR1; NR3C1; MYOCD; MKL1; MKL2; PSME3; UBE3A; TP53; RARA; MAPK1; PIN1; PGR; EP300; ELAVL1; MAPK14; CREBBP; CEBPD; CEBPA; TP53BP1; TFF1; PSMC5; PSMA3; PRKC

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.