REST Antibody - middle region: Biotin (ARP32478_P050-Biotin)

REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described; however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

BTRC; UBC; FBXW11; CSNK1E; NEDD8; EHMT2; EIF4A3; FBXW4; FBXW7; FBXW5; FBXW8; FBXW2; SIN3A; TERF2; GRIA2; SUB1; GTF2B; Tbp; SIN3B; HDAC1; RCOR1; SP1; SMARCE1; SMARCC2; SMARCA4; CDYL; HDAC5; HDAC4; HTT; NCOR1; KDM5C; RNF2; HDAC2; STMN2; GRM2; CTDSP1

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.