NCOR2 Antibody - N-terminal region: Biotin (ARP32464_T100-Biotin)
Product Specifications
Gene Name
Nuclear receptor corepressor 2
Gene Aliases
SMRT, TRAC, CTG26, SMRTE, TRAC1, N-CoR2, TNRC14, TRAC-1, SMAP270, SMRTE-tau
Gene ID
9612
Swiss Prot
Q9Y618
Accession Number
NP_006303
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NCOR2
Target
NCOR2 forms a large corepressor complex that contains SIN3A/B and histone deacetylases HDAC1 and HDAC2. This complex associates with the thyroid (TR) and the retinoid acid receptors (RAR) in the absence of ligand, and may stabilize their interaction with TFIIB. NCOR2 mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Partner Proteins
HDAC4; HDAC3; RARA; HMGA1; HDAC2; HDAC1; AURKA; BCL6; BCOR; GPS2; ZBTB16; UBC; E2F1; NR1I2; BTRC; HDAC7; NR1H2; THRA; RUNX1; Pparg; Nr2f1; Nr1i3; Nr2f2; CBX6; C1D; NR1H4; NR1D1; Ppard; SUMO2; CTBP1; ARNT; AHR; NCOR1; AR; NRD1; E2F4; ZBTB7A; SOX2; ESR1; CE
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Sample Type
NCOR2 is supported by BioGPS gene expression data to be expressed in HeLa
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 86%; Human: 100%; Mouse: 79%; Pig: 79%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
275kDa
Shipping Conditions
Wet Ice
Protein Length
2524
NCBI Gene Symbol
NCOR2
Protein Name
Nuclear receptor corepressor 2
Nucleotide Accession Number
NM_006312
Curated Selection
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