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Pcbd1 Antibody - C-terminal region: Biotin (ARP32448_P050-Biotin)

Product Specifications

Gene Name

Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1

Gene Aliases

Dco, Pcb, Pcd, Phs, Dcoh, Pcbd

Gene ID

13180

Swiss Prot

P61458

Accession Number

NP_079549

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Target

Pcbd1 is involved in tetrahydrobiopterin biosynthesis. It seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. It is a coactivator for HNF1A-dependent transcription. It regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity.

Partner Proteins

Pcbd2; Hnf1a; Zdhhc13; Pawr; Tle6; Chd4; Asb15; Brpf1; Cers2; Ercc8; Asb3; Zfp110; Hnf1b; Srebf1; Polr1a; Pcbd1; Zfp36l1; Bard1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 82%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

12kDa

Shipping Conditions

Wet Ice

Protein Length

104

NCBI Gene Symbol

PCBD1

Protein Name

Pterin-4-alpha-carbinolamine dehydratase

Nucleotide Accession Number

NM_025273

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