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PAX3 Antibody - middle region : FITC (ARP32446_T100-FITC)

Selected Variant

ARP32446_T100-FITC

Size: 100 µL

Product Specifications

Gene Name

Paired box 3

Gene Aliases

WS1, WS3, CDHS, HUP2

Gene ID

5077

Swiss Prot

Q86UQ3

Accession Number

NP_852126

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PAX3

Target

PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2;13) (q35; q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.

Partner Proteins

PCTP; UBC; TAF1; POU3F2; HDAC1; TRIM28; HDAC10; SOX8; WWTR1; PAX3; DAXX; CIB1; SOX10; MEOX2; MEOX1; MITF; MSX1; Rad23b; PSMD4; TBP; IPO13; CNR1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Wachtel, M., et al., (2004) Cancer Res. 64 (16), 5539-5545

Shipping Conditions

Wet Ice

Protein Length

403

NCBI Gene Symbol

PAX3

NCBI GB Accession Number

PAX3

Host or Source

Rabbit

Protein Name

Paired box protein Pax-3

Nucleotide Accession Number

NM_181461

Peptide Sequence

KGEEEEADLERKEAEESEKKAKHSIDGILSERASAPQSDEGSDIDSEPDL

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