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ZEB1 Antibody - N-terminal region : FITC (ARP32422_P050-FITC)

Selected Variant

ARP32422_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Zinc finger E-box binding homeobox 1

Gene Aliases

BZP, TCF8, AREB6, FECD6, NIL2A, PPCD3, ZFHEP, ZFHX1A, DELTAEF1

Gene ID

6935

Swiss Prot

P37275

Accession Number

NP_110378

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ZEB1

Target

ZEB1 is a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site.ZEB1 encodes a zinc finger transcription factor that represses T-lymphocyte-specific IL2 gene (MIM 147680) expression by binding to a negative regulatory domain 100 nucleotides 5-prime of the IL2 transcription start site (Williams et al., 1991 [PubMed 1840704]) .[supplied by OMIM].

Partner Proteins

SUMO1; CDK6; GTF2A1; UBR4; SUMO2; SIRT1; SOX2; CTBP2; CTBP1; SMAD7; SMAD6; SMARCA4; SERPINH1; SMAD3; EP300; DRAP1; KAT5; SMAD2; SMAD1; CDH1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IF, WB

Purification

Affinity Purified

Sample Type

ZEB1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

124kDa

References & Citations

Gregory, P.A., (2008) Nat. Cell Biol. 10 (5), 593-601

Shipping Conditions

Wet Ice

Protein Length

1124

NCBI Gene Symbol

ZEB1

NCBI GB Accession Number

ZEB1

Host or Source

Rabbit

Protein Name

Zinc finger E-box-binding homeobox 1

Nucleotide Accession Number

NM_030751

Peptide Sequence

KDDECESDAENEQNHDPNVEEFLQQQDTAVIFPEAPEEDQRQGTPEASGH

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