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SIRT7 Antibody - C-terminal region : HRP (ARP32406_P050-HRP)

Selected Variant

ARP32406_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Sirtuin 7

Gene Aliases

SIR2L7

Gene ID

51547

Swiss Prot

Q9NRC8

Accession Number

NP_057622

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT7

Target

SIRT7 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT7 is included in class IV of the sirtuin family.

Partner Proteins

DDB1; VPRBP; APP; NOL6; YTHDC2; DDX31; RBM15; ANAPC1; NSD1; NOC3L; UBE2O; RBM25; CCAR2; CHD8; BEND3; PHRF1; DHX37; NUFIP2; CGN; XPO5; LRRC47; BIRC6; WDR18; THOC2; NUP107; REXO4; DDX24; XAB2; UGGT1; ZC3HAV1; YLPM1; NKRF; CCT5; SNW1; DHX30; DIS3; PUF60; COP

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

45kDa

References & Citations

Mahon, P.C., et al., (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798

Shipping Conditions

Wet Ice

Protein Length

400

NCBI Gene Symbol

SIRT7

NCBI GB Accession Number

SIRT7

Host or Source

Rabbit

Protein Name

NAD-dependent protein deacetylase sirtuin-7

Nucleotide Accession Number

NM_016538

Peptide Sequence

DVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREE

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