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LEF1 Antibody - C-terminal region : HRP (ARP32403_T100-HRP)

Selected Variant

ARP32403_T100-HRP

Size: 100 µL

Product Specifications

Gene Name

Lymphoid enhancer-binding factor 1

Gene Aliases

LEF-1, TCF10, TCF7L3, TCF1ALPHA

Gene ID

51176

Swiss Prot

Q9UJU2

Accession Number

NP_057353

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human LEF1

Target

Lymphoid enhancer-binding factor-1 (LEF1) is a 48-kD nuclear protein that is expressed in pre-B and T cells. It binds to a functionally important site in the T-cell receptor-alpha enhancer and confers maximal enhancer activity. LEF1 belongs to a family of regulatory proteins that share homology with high mobility group protein-1.

Partner Proteins

RNF138; UBC; RNF14; NLK; NARF; STAT5A; PITX2; CTNNB1; CDX1; DPYSL2; nrarp; FHIT; MITF; HINT1; TLE2; TLE1; SETD8; MYB; E2F1; HDAC1; ZBTB3; DACT1; DAZAP2; ALYREF; PIAS4; ALX4; SMAD3; SUMO2; EP300; SMAD1; SMAD2; SMAD4; KPNA1; KPNA2; UBTF; RUNX2; NOTCH1; RUVB

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

LEF1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

References & Citations

Liu, X., et al., (2004) J. Invest. Dermatol. 123 (2), 264-274

Shipping Conditions

Wet Ice

Protein Length

399

NCBI Gene Symbol

LEF1

NCBI GB Accession Number

LEF1

Host or Source

Rabbit

Protein Name

Lymphoid enhancer-binding factor 1

Nucleotide Accession Number

NM_016269

Peptide Sequence

VKPQHEQRKEQEPKRPHIKKPLNAFMLYMKEMRANVVAECTLKESAAINQ

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