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PAX7 Antibody - N-terminal region : Biotin (ARP32392_P050-Biotin)

Selected Variant

ARP32392_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Paired box 7

Gene Aliases

HUP1, RMS2, PAX7B, MYOSCO

Gene ID

5081

Swiss Prot

P23759

Accession Number

NP_002575

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PAX7

Target

PAX7 is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box gene 7 is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown. This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Alternative splicing in this gene has produced two known products but the biological significance of the variants is unknown.

Partner Proteins

TRIM27; MYOD1; Dlg4; WDR5; ASH2L; HIRA; Ubc

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 91%; Horse: 100%; Human: 100%; Mouse: 75%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

References & Citations

Moller, E., (2007) Cancer Genet. Cytogenet. 178 (2), 114-119

Shipping Conditions

Wet Ice

Protein Length

520

NCBI Gene Symbol

PAX7

NCBI GB Accession Number

PAX7

Host or Source

Rabbit

Protein Name

Paired box protein Pax-7

Nucleotide Accession Number

NM_002584

Peptide Sequence

CDRSTVPSGLVSSISRVLRIKFGKKEEEDEADKKEDDGEKKAKHSIDGIL

Price

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