SIRT5 Antibody - C-terminal region : Biotin (ARP32390_P050-Biotin)
Product Specifications
Gene Name
Sirtuin 5
Gene Aliases
SIR2L5
Gene ID
23408
Swiss Prot
Q9NXA8
Accession Number
NP_112534
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT5
Target
SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.
Partner Proteins
SIRT3; UBC; HECW2; APP; RELA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Goat: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
References & Citations
Frye, R.A. (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798
Shipping Conditions
Wet Ice
Protein Length
299
NCBI Gene Symbol
SIRT5
NCBI GB Accession Number
SIRT5
Host or Source
Rabbit
Protein Name
NAD-dependent protein deacylase sirtuin-5, mitochondrial
Nucleotide Accession Number
NM_031244
Peptide Sequence
EVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATN
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