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SIRT5 Antibody - C-terminal region : FITC (ARP32390_P050-FITC)

Selected Variant

ARP32390_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Sirtuin 5

Gene Aliases

SIR2L5

Gene ID

23408

Swiss Prot

Q9NXA8

Accession Number

NP_112534

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SIRT5

Target

SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.

Partner Proteins

SIRT3; UBC; HECW2; APP; RELA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Goat: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 93%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

32kDa

References & Citations

Frye, R.A. (2000) Biochem. Biophys. Res. Commun. 273 (2), 793-798

Shipping Conditions

Wet Ice

Protein Length

299

NCBI Gene Symbol

SIRT5

NCBI GB Accession Number

SIRT5

Host or Source

Rabbit

Protein Name

NAD-dependent protein deacylase sirtuin-5, mitochondrial

Nucleotide Accession Number

NM_031244

Peptide Sequence

EVDRELAHCDLCLVVGTSSVVYPAAMFAPQVAARGVPVAEFNTETTPATN

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