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TLE4 Antibody - N-terminal region: Biotin (ARP32381_P050-Biotin)

Product Specifications

Gene Name

Transducin-like enhancer of split 4 (E (sp1) homolog, Drosophila)

Gene Aliases

ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E (spI), E (spl)

Gene ID

7091

Swiss Prot

Q04727

Accession Number

NP_008936

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Target

TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

Partner Proteins

SRPK2; POU2F2; UBC; LIG4; BRCA1; WDR77; PRMT5; PPM1B; CUX1; OTX1; OTX2; TLE4; PAX5; POU2F1; MSX1; HDAC1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

84kDa

Shipping Conditions

Wet Ice

Protein Length

773

NCBI Gene Symbol

TLE4

Protein Name

Transducin-like enhancer protein 4

Nucleotide Accession Number

NM_007005

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