TLE4 Antibody - N-terminal region : Biotin (ARP32381_P050-Biotin)

Product Specifications

Gene Name

Transducin-like enhancer of split 4 (E (sp1) homolog, Drosophila)

Gene Aliases

ESG, BCE1, ESG4, GRG4, BCE-1, Grg-4, E (spI), E (spl)

Gene ID

7091

Swiss Prot

Q04727

Accession Number

NP_008936

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TLE4

Target

TLE4 is the transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

Partner Proteins

SRPK2; POU2F2; UBC; LIG4; BRCA1; WDR77; PRMT5; PPM1B; CUX1; OTX1; OTX2; TLE4; PAX5; POU2F1; MSX1; HDAC1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.