RUVBL2 Antibody - N-terminal region : Biotin (ARP32378_T100-Biotin)

Product Specifications

Gene Name

RuvB-like 2 (E. coli)

Gene Aliases

RVB2, TIH2, ECP51, TIP48, CGI-46, ECP-51, INO80J, REPTIN, TIP49B, TAP54-beta

Gene ID

10856

Swiss Prot

Q9Y230

Accession Number

NP_006657

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human RUVBL2

Target

RuvB-Like 2 (48-kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.

Partner Proteins

CCDC103; LNX1; RUVBL1; UBC; DPCD; HUWE1; VCP; SUMO2; RPAP3; MDM2; RPA3; RPA2; RPA1; SUZ12; EED; RNF2; BMI1; CDKN2A; ASNA1; PPP6R3; PLA2G4A; PARK2; FBXO6; TARDBP; YWHAQ; PPP6R2; EXOSC10; BAG3; POLR2E; UPF1; SMG1; RBM8A; TTI1; PAN2; TBP; CTNNB1; STOM; RUVBL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

RUVBL2 is supported by BioGPS gene expression data to be expressed in Daudi

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.