HES1 Antibody - N-terminal region : Biotin (ARP32372_T100-Biotin)
Product Specifications
Gene Name
Hairy and enhancer of split 1, (Drosophila)
Gene Aliases
HHL, HRY, HES-1, bHLHb39
Gene ID
3280
Swiss Prot
Q14469
Accession Number
NP_005515
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human HES1
Target
HES1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Partner Proteins
STAT3; JAK2; APH1A; LTBR; ASGR2; TLE1; ELAVL1; PARP1; UBC; NUDT3; HDAC6; YWHAB; PTK2; NR4A1; HMGCL; GAPDH; FHL1; CSNK1E; APCS; FANCE; FANCC; FANCA; FANCL; SPTAN1; HSP90AA1; HSPA4; FANCG; FANCF; HDAC1; RUNX2; HES6; ID4; ID1; SIRT1; UBQLN1; HEY2; ID2; ID3
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IF, IP, WB, IHC
Sample Type
HES1 is strongly supported by BioGPS gene expression data to be expressed in Raji
Concentration
0.5 mg/ml
Homology
Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
30kDa
References & Citations
Hoebeke, I., et al., (2006) Blood 107 (7), 2879-2881
Shipping Conditions
Wet Ice
Protein Length
280
NCBI Gene Symbol
HES1
NCBI GB Accession Number
HES1
Host or Source
Rabbit
Protein Name
Transcription factor HES-1
Nucleotide Accession Number
NM_005524
Peptide Sequence
NTTPDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSR
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