TBX19 Antibody - N-terminal region : FITC (ARP32363_T100-FITC)
Selected Variant
ARP32363_T100-FITC
Size: 100 µL
Product Specifications
Gene Name
T-box 19
Gene Aliases
TPIT, TBS19, dJ747L4.1
Gene ID
9095
Swiss Prot
O60806
Accession Number
NP_005140
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human TBX19
Target
TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX19 is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC) -expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.
Partner Proteins
NR5A1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, WB
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
48kDa
References & Citations
Maira, M., et al., (2003) J.Biol.Chem.278 (47),46523-46532
Shipping Conditions
Wet Ice
Protein Length
448
NCBI Gene Symbol
TBX19
NCBI GB Accession Number
TBX19
Host or Source
Rabbit
Protein Name
T-box transcription factor TBX19
Nucleotide Accession Number
NM_005149
Peptide Sequence
KPSDGTVSHLLNVVESELQAGREKGDPTEKQLQIILEDAPLWQRFKEVTN
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