TLE2 Antibody - N-terminal region : Biotin (ARP32347_P050-Biotin)

Product Specifications

Gene Name

Transducin-like enhancer of split 2 (E (sp1) homolog, Drosophila)

Gene Aliases

ESG, ESG2, GRG2

Gene ID

7089

Swiss Prot

Q04725

Accession Number

NP_003251

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human TLE2

Target

TLE2 belongs to the WD repeat Groucho/TLE family. It contains 6 WD repeats. TLE2 is a transcriptional corepressor that binds to a number of transcription factors. It inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.

Partner Proteins

UBC; SUMO1; ORF50; LEF1; BARHL1; TLX3; VENTX; CUL4A; CUL4B; PAX9; MSX2; MSX1; FOXA3; EMX2; PRDM1; H3F3B; TLE1; UTY; HMGB1; RUNX1; TLE2; HES1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 85%; Pig: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.