NKX2-2 Antibody - N-terminal region : Biotin (ARP32338_P050-Biotin)
Product Specifications
Gene Name
NK2 homeobox 2
Gene Aliases
NKX2B, NKX2.2
Gene ID
4821
Swiss Prot
O95096
Accession Number
NP_002500
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human NKX2-2
Target
Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2. Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.
Partner Proteins
Dlg4; SIN3A; HDAC1; OLIG2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
IHC, WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 100%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
30kDa
References & Citations
Owen, L.A., (er) PLoS ONE 3 (4), E1965 (2008)
Shipping Conditions
Wet Ice
Protein Length
273
NCBI Gene Symbol
NKX2-2
NCBI GB Accession Number
NKX2-2
Host or Source
Rabbit
Protein Name
Homeobox protein Nkx-2.2
Nucleotide Accession Number
NM_002509
Peptide Sequence
MSLTNTKTGFSVKDILDLPDTNDEEGSVAEGPEEENEGPEPAKRAGPLGQ
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